Hydrocodone vs Oxycodone: What’s the Difference?

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Hydrocodone along with Oxycodone are painkillers prescribed by doctors that are part of the opioid pain relief medications. They are used to treat severe or moderate pain, as well as acute pain that is triggered by the treatment of cancer, chemotherapy and other pain. Learn more about the many similarities and differences in hydrocodone and buy Hydrocodone.

What are the similarities between hydrocodone as well as Oxycodone?


Both are semi-synthetic drugs that are narcotic painkillers made up of morphine created in a lab. Both of these drugs are used to treat pain that is severe in combination with non-narcotic pain medicines such as acetaminophen (Tylenol) or Ibuprofen (Advil, Motrin). These prescription medicines are generally utilized to provide temporary relief from discomfort. For instance, hydrocodone or Oxycodone prescriptions are usually utilized to treat pain after major surgery or an injury such as fracture. Opioids like hydrocodone and Oxycodone are also used to treat severe pain caused by advanced cancer. Opioids like these and others are prescribed to treat chronic and severe pain in patients who suffer from kidney impairment which is not a suitable candidate for NSAIDs or painkillers for nerves like gabapentin.


They are both offered in generic versions with lower prices in addition to brand-name versions. These can serve on their own as a standalone product, or in conjunction with other non-narcotic pain medicines such as acetaminophen and aspirin and Ibuprofen. The dosage options to Oxycodone and hydrocodone include immediate-release and extended-release tablets, capsules or liquid solution. The immediate-release ones are consumed every four to six hours. The extended-release varieties are consumed once every 12 hours to alleviate discomfort.


Both Oxycodone and hydrocodone are similar in their way of working. Both substances ease discomfort by binding with opioid receptors in the central nervous system of the brain and thereby blocking pain signals. Hydrocodone, along with Oxycodone can affect the reward system in the brain. They alter the way you feel about pain.


Studies have shown it is true that Oxycodone and hydrocodone both work effectively to ease pain temporarily.


Certain side effects associated with Oxycodone and hydrocodone are the same which include constipation, nausea dry mouth, insomnia and headache.


Another feature that is shared among Oxycodone as well as hydrocodone, is that abruptly stopping both of them could trigger withdrawal symptoms for addicts who use opioids.


Hydrocodone and Oxycodone are both used for the treatment of small to moderate pain. These aren’t the preferred treatment for chronic or long-term pain as they’re fast-acting and could turn into a very addictive habit that can be hard to break.”

It’s therefore only for those with chronic pain who are unable to tolerate other types of pain medication.

Hydrocodone and Oxycodone have been classified as Schedule II drugs due to their potential for psychological and physical dependence that could result in addiction and addiction. Abuse of oxycodone or hydrocodone is linked with a substantial risk of developing a drug-seeking behaviour and an addiction to opioids. Opioid addiction could cause serious health issues, including overdoses, and possibly death.


Use of oxycodone or hydrocodone may increase the likelihood of respiratory depression that can be life-threatening. It is which can cause breathing problems, causing the breath to become very thin. It can lead to death if untreated. This risk is increased when you are taking other medications with similar effects, or if you have an underlying lung disease.

Other serious but uncommon adverse reactions to Oxycodone and hydrocodone may include hallucinations, chest pain and agitation, as well as confusion. heartbeats that are rapid or slow muscles, muscle tension, muscle twitching; nausea vomiting, shivering vomiting; loss of appetite or weakness. Also, it can cause dizziness; decreased sexual desire, irregular menstrual cycle, as and allergic reactions that cause swelling of the eyes, face mouth or throat, and a skin rash that causes hives, itching, and difficulty breathing or swallowing.

Utilizing these two drugs together with other medicines from the opioid class can be a risk in pregnancy and can cause congenital disability. Opioid drugs shouldn’t be used to treat pain during breastfeeding as they can infiltrate breastmilk of mothers and cause harm to the infant.

What are the major difference between hydrocodone and Oxycodone?

Here are some distinctions of hydrocodone and Oxycodone:

Oxycodone is more potent than hydrocodone on a milligram-to-milligram basis. However, both drugs offer the same amount for pain reduction.

Hydrocodone can trigger constipation, fatigue, issues with urinary tracts, tightening of muscles and sleep problems as potential adverse effects. It is known to cause adverse effects, such as flushing or mood swings. However, each person’s experience with a specific drug could be different. There are occasions where you can take some medications, like hydrocodone or Oxycodone more than the other and have lesser negative adverse consequences.

The half-life of Oxycodone can be as long as 2.6 hours. The duration of use for hydrocodone is expected to take 4.2 hours. Half-life is the amount of time that it takes for the body to get rid of just half the amount that is initially taken in by the drug. Because hydrocodone stays longer in your body as well as being more powerful than other drugs, it is more likely to have a risk of dependence and misuse. However, both hydrocodone and Oxycodone fall into Schedule II drugs which are prone to addiction.

Take note that the information on drugs should not replace the guidance of a medical professional. If you have additional questions or wish to know the best option for you, oxycodone or. hydrocodone, consult your physician or pharmacist.

Frequently Asked Questions


Opioids like hydrocodone, morphine codeine, oxycodone, tramadol and fentanyl are among the most powerful pain relieving drugs available to treat acute or chronic pain. Fentanyl can be described as an synthetic opioid that’s between 50 to 100 times more potent as morphine which, in turn is a natural opioid. It is one of the most powerful painkillers. It is used to treat severe pain, such as pain caused by cancer that is advanced.


A double-masked controlled research study that was randomized found that Oxycodone was approximately 1.5 times more effective than buy hydrocodone online. However, both medications provide adequate pain relief.


There is no controlled substance under the class IV. A tiny, double-masked random study revealed it to be Oxycodone can be eight times more powerful than tramadol.What’s the difference between OXYCONTIN AND OXYCODONE? Oxycodone brand is generic drug. OxyContin is a brand name product which contains Oxycodone as the active ingredient. OxyContin is a controlled-release formulation that offers continuous, 24 hour relief from pain.

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